Canterbury DHB

Context

Presumed Septicaemia

Post-abdominal surgery

cefuroxime

HMLSchedNZFPMLnoids

IV 1.5 g every eight hours

AND

gentamicin

HMLSchedNZFPMLnoids

IV 5 to 7 mg/kg ideal body weight initially, then see dosing guidelines.

AND

metronidazole

HMLSchedNZFPMLnoids

IV 500 mg every twelve hours

Severe penicillin allergy – consult with Infectious Diseases/Clinical Microbiology

If multi-drug resistant organism isolated or suspected give

piperacillin+tazobactam

HMLNZFPMLnoids

(Tazocin™)

IV 4 g/500 mg every eight hours

OR

meropenem

HMLNZFPMLnoids

IV 1 g every eight hours

Post-orthopaedic surgery

flucloxacillin

HMLSchedNZFPMLnoids

IV 2 g every six hours

PLUS

gentamicin

HMLSchedNZFPMLnoids

IV 5 to 7 mg/kg ideal body weight initially. See dosing guidelines

Mild penicillin allergy

cefazolin

HMLSchedNZFPMLnoids

IV 2 g every eight hours

PLUS

gentamicin

HMLSchedNZFPMLnoids

IV 5 to 7 mg/kg ideal body weight initially, then see dosing guidelines.

Information about this Canterbury DHB document (99283):

Document Owner:

Not assigned (see Who's Who)

Last Updated:

October 2016 (Surgical Post-operative Antimicrobial Guidelines)

Next Review Due:

October 2019

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document.

Topic Code: 99283