Canterbury DHB

Context

Necrotising Soft Tissue Infections

Pathogens

Drug Treatment

Empiric

Limb infection:

flucloxacillin

HMLSchedNZFPMLnoids

IV 2 g every four hours

AND

clindamycin

HMLSchedNZFPMLnoids

IV 600 mg every eight hours

Penicillin allergy

Consult Infectious Diseases/Clinical Microbiology

Abdominal/perineal infection:

piperacillin+tazobactam

HMLNZFPMLnoids

IV 4 g/500 mg every eight hours

AND

clindamycin

HMLSchedNZFPMLnoids

IV 600 mg every eight hours

Penicillin allergy

Consult Infectious Diseases/Clinical Microbiology

Pathogens Known

Streptococcus pyogenes, Clostridium perfringens

benzylpenicillin

HMLSchedNZFPMLnoids

(Penicillin G)

IV 1.8 g (3 megaunits) every four hours

AND

clindamycin

HMLSchedNZFPMLnoids

IV 600 mg every eight hours

Mild penicillin allergy

cefazolin

HMLSchedNZFPMLnoids

IV 2 g every eight hours

AND

clindamycin

HMLSchedNZFPMLnoids

IV 600 mg every eight hours

Severe penicillin allergy

Consult Infectious Diseases / Clinical Microbiology

Information about this Canterbury DHB document (99266):

Document Owner:

Not assigned (see Who's Who)

Last Updated:

March 2018 (Skin and Soft Tissue)

Next Review Due:

March 2021

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document.

Topic Code: 99266