Canterbury DHB

Context

Infected Ulcers (e.g. diabetic, vascular, pressure)

Pathogens

Drug Treatment

Empiric

Mild to moderate infection

amoxicillin+clavulanic acid

HMLSchedNZFPMLnoids

IV 1 g/200 mg every eight hours then PO 500 mg/125 mg three times a day

Mild penicillin allergy

cefuroxime

HMLSchedNZFPMLnoids

IV 1.5 g every eight hours

AND

metronidazole

HMLSchedNZFPMLnoids

PO 600 mg twice a day

followed by

cefalexin

HMLSchedNZFPML

PO 500 mg four times a day

AND

metronidazole

HMLSchedNZFPMLnoids

PO 600 mg twice a day

Severe penicillin allergy

ciprofloxacin

HMLSchedNZFPMLnoids

PO 500 mg twice a day

AND

clindamycin

HMLSchedNZFPMLnoids

PO 450 mg three times a day

Severe infection

piperacillin+tazobactam

HMLNZFPMLnoids

IV 4 g/500 mg every eight hours

Mild penicillin allergy

meropenem

HMLNZFPMLnoids

IV 1 g every eight hours

Severe penicillin allergy

Consult Infectious Diseases/Clinical Microbiology

Information about this Canterbury DHB document (99261):

Document Owner:

Not assigned (see Who's Who)

Last Updated:

March 2018 (Skin and Soft Tissue)

Next Review Due:

March 2021

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document.

Topic Code: 99261