Canterbury DHB

Context

Pelvic Inflammatory Disease

Pathogens

Drug Treatment

Empiric

Mild/Moderate disease

If GI side effects with the below combinations are too severe - stop metronidazole.

ceftriaxone

HMLSchedNZFPMLnoids

IM 500 mg stat

AND

metronidazole

HMLSchedNZFPMLnoids

PO 400 mg twice a day for 2 weeks

AND EITHER

doxycycline

HMLSchedNZFPML

PO 100 mg twice a day for 2 weeks

OR, if pregnant or non-compliant

azithromycin

HMLSchedNZFPML

PO 1000 mg stat weekly for 2 weeks

Severe penicillin allergy

gentamicin

HMLSchedNZFPMLnoids

IV 5 mg/kg ideal body weight single dose

AND

metronidazole

HMLSchedNZFPMLnoids

PO 400 mg twice a day for 2 weeks

AND

doxycycline

HMLSchedNZFPML

PO 100 mg twice a day for 2 weeks

Failed/Severe disease

ceftriaxone

HMLSchedNZFPMLnoids

IV 1 g every 24 hours

AND

metronidazole

HMLSchedNZFPMLnoids

IV 500 mg every twelve hours

or PO 600 mg twice a day

AND EITHER

doxycycline

HMLSchedNZFPML

PO 100 mg twice a day for 2 weeks

OR, if pregnant

erythromycin ethylsuccinate

HMLSchedPML

PO 800 mg four times a day for 2 weeks

Severe penicillin allergy

clindamycin

HMLSchedNZFPMLnoids

IV 600 mg every eight hours

AND

gentamicin

HMLSchedNZFPMLnoids

See dosing guidelines

followed by

doxycycline

HMLSchedNZFPML

PO 100 mg twice a day for 2 weeks

AND

metronidazole

HMLSchedNZFPMLnoids

PO 400 mg twice a day for 2 weeks

Information about this Canterbury DHB document (99241):

Document Owner:

Not assigned (see Who's Who)

Last Updated:

May 2019 (Obstetrics and Gynaecology)

Next Review Due:

May 2022

Keywords:

Note: Only the electronic version is controlled. Once printed, this is no longer a controlled document.

Topic Code: 99241